Pooja R. Mohobe, Doyel M. Bhattacharya, Himani C. Pandhurnekar and Sunil L. Dahire
Published in Vol.15, 2025
KEYWORDS: β-diketones, Metal complexes, Baker-Venkataraman rearrangement, Antibacterial activity, thermogravimetric analysis.
ABSTRACT:
1-(2,4-dihydroxy-5-nitrophenyl)-3-(thiophen-2-yl)propane-1,3-dione (DNTPD) and its Calcium and Magnesium complexes have been synthesized. The β-diketone ligand is afforded by employing Baker-Venkataraman rearrangement on 4-hydroxy-5-nitro-2-(thiophen-2-yl) oxyacetophenone which was previously synthesized by p-nitroresacetophenone and thiophene-2-carboxylic acid. The synthesized compounds were characterized by their physical properties, elemental analysis, IR spectra, 1H-NMR, mass spectra and electronic spectra and the geometry of metal complexes have been concluded by magnetic spectra. The thermal stability of metal complexes has been studied by Thermogravimetric analysis. The ligand and its transition metal complexes have been studied under pathogenic bacteria like Staphylococcus aureus, Bacillus subtilis, Proteus vulgaris, Escherichia coli and Proteus aeruginosa by filter paper disc diffusion method.
DOI: https://doi.org/10.64833/hislopia.j.vol.15.issue1.105-115